Inhibition of Nb2 T-lymphoma cell growth by transforming growth factor-beta.
نویسندگان
چکیده
Transforming growth factor-beta (TGF-beta) inhibits proliferation of Nb2 cells, a rat T lymphoma, in response to lactogens and interleukin-2. Prostaglandins may play an important role in the pathway through which TGF-beta exerts its inhibitory actions, because prostaglandin E2 also inhibits proliferation of Nb2 cells, and indomethacin, an inhibitor of prostaglandin synthesis, reverses the inhibitory effects of TGF-beta on Nb2 cell proliferation.
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عنوان ژورنال:
- The Biochemical journal
دوره 253 1 شماره
صفحات -
تاریخ انتشار 1988